Ozzy & Drix

菲尔·拉马

Osmosis Jones (voice)

杰夫·本内特

Drix (voice)

阿兰娜·乌巴赫

Mayor Paul Spryman / Hector's Mom (voice)

Justin Cowden

Hector Cruz (voice)

Tasia Valenza

Maria Amino (voice)

吉姆·卡明斯

Police Chief Gluteus (voice)